MCD First Exam Reading List for June 2021 First Level Exam:

  1. Andersen, K.G., Rambaut, A., Lipkin, W.I., Holmes, E.C., and Garry, R.F. (2020). The proximal origin of SARS-CoV-2. Nat Med 26, 450-452.
  2. Barkess, G., and West, A.G. (2012). Chromatin insulator elements: establishing barriers to set heterochromatin boundaries. Epigenomics 4, 67-80.
  3. Corces, M.R., Buenrostro, J.D., Wu, B., Greenside, P.G., Chan, S.M., Koenig, J.L., Snyder, M.P., Pritchard, J.K., Kundaje, A., Greenleaf, W.J., et al. (2016). Lineage-specific and single-cell chromatin accessibility charts human hematopoiesis and leukemia evolution. Nat Genet 48, 1193-1203.
  4. Dufrene, Y.F., and Persat, A. (2020). Mechanomicrobiology: how bacteria sense and respond to forces. Nat Rev Microbiol 18, 227-240.
  5. Eraslan, G., Avsec, Z., Gagneur, J., and Theis, F.J. (2019). Deep learning: new computational modelling techniques for genomics. Nat Rev Genet 20, 389-403.
  6. Gasperini, M., Tome, J.M., and Shendure, J. (2020). Towards a comprehensive catalogue of validated and target-linked human enhancers. Nat Rev Genet 21, 292-310.
  7. Hjortness, M.K., Riccardi, L., Hongdusit, A., Zwart, P.H., Sankaran, B., De Vivo, M., and Fox, J.M. (2018). Evolutionarily Conserved Allosteric Communication in Protein Tyrosine Phosphatases. Biochemistry 57, 6443-6451.
  8. Kampinga, H.H., and Craig, E.A. (2010). The HSP70 chaperone machinery: J proteins as drivers of functional specificity. Nat Rev Mol Cell Biol 11, 579-592.
  9. Keedy, D.A., Hill, Z.B., Biel, J.T., Kang, E., Rettenmaier, T.J., Brandao-Neto, J., Pearce, N.M., von Delft, F., Wells, J.A., and Fraser, J.S. (2018). An expanded allosteric network in PTP1B by multitemperature crystallography, fragment screening, and covalent tethering. Elife 7.
  10. Liu, Z., Shi, H., Nzessi, A.K., Norris, A., Grant, B.D., and Liu, J. (2020). Tetraspanins TSP-12 and TSP-14 function redundantly to regulate the trafficking of the type II BMP receptor in Caenorhabditis elegans. Proc Natl Acad Sci U S A 117, 2968-2977.
  11. Marteijn, J.A., Lans, H., Vermeulen, W., and Hoeijmakers, J.H. (2014). Understanding nucleotide excision repair and its roles in cancer and ageing. Nat Rev Mol Cell Biol 15, 465-481.
  12. Nora, E.P., Goloborodko, A., Valton, A.L., Gibcus, J.H., Uebersohn, A., Abdennur, N., Dekker, J., Mirny, L.A., and Bruneau, B.G. (2017). Targeted Degradation of CTCF Decouples Local Insulation of Chromosome Domains from Genomic Compartmentalization. Cell 169, 930-944 e922.
  13. Pines, A., Dijk, M., Makowski, M., Meulenbroek, E.M., Vrouwe, M.G., van der Weegen, Y., Baltissen, M., French, P.J., van Royen, M.E., Luijsterburg, M.S., et al. (2018). TRiC controls transcription resumption after UV damage by regulating Cockayne syndrome protein A. Nat Commun 9, 1040.
  14. Ponisch, W., Eckenrode, K.B., Alzurqa, K., Nasrollahi, H., Weber, C., Zaburdaev, V., and Biais, N. (2018). Pili mediated intercellular forces shape heterogeneous bacterial microcolonies prior to multicellular differentiation. Sci Rep 8, 16567.
  15. Rodriguez-Gonzalez, C., Lin, S., Arkan, S., and Hansen, C. (2020). Co-chaperones DNAJA1 and DNAJB6 are critical for regulation of polyglutamine aggregation. Sci Rep 10, 8130.
  16. Sato, K., Norris, A., Sato, M., and Grant, B.D. (2014). C. elegans as a model for membrane traffic. WormBook, 1-47.Wallace, J.A., and Felsenfeld, G. (2007). We gather together: insulators and genome organization. Curr Opin Genet Dev 17, 400-407.
  17. Wallace, J.A., and Felsenfeld, G. (2007). We gather together: insulators and genome organization. Curr Opin Genet Dev 17, 400-407.
  18. Wei, P.C., Chang, A.N., Kao, J., Du, Z., Meyers, R.M., Alt, F.W., and Schwer, B. (2016). Long Neural Genes Harbor Recurrent DNA Break Clusters in Neural Stem/Progenitor Cells. Cell 164, 644-655.
  19. Weissman, I.L., and Gage, F.H. (2016). A Mechanism for Somatic Brain Mosaicism. Cell 164, 593-595.
  20. Yao, H., Song, Y., Chen, Y., Wu, N., Xu, J., Sun, C., Zhang, J., Weng, T., Zhang, Z., Wu, Z., et al. (2020). Molecular Architecture of the SARS-CoV-2 Virus. Cell 183, 730­738 e713.
  21. Zou, J., Huss, M., Abid, A., Mohammadi, P., Torkamani, A., and Telenti, A. (2019). A primer on deep learning in genomics. Nat Genet 51, 12-18.

MCD 2021 First Level Exam Instructions:
Monday June 14th is the date for the MCD First Level Exam.
The morning essay writing session is from 9am-12pm.
The afternoon experimental design and data analysis session is from 2pm-5pm.

Last Updated ( Thursday, 04 February 2021 18:47 )